Biomimetic nano drug delivery carriers for treating cardiovascular diseases

Inspired by the way cells in our body respond to CVD pathologies, biomimetic nanoparticles hold great promise. Progress in biomimetic nanoparticle engineering design principles, including surface engineering and morphology engineering, will advance this field to discover novel, exciting therapeutic solutions.
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RNA therapeutics have the potential to transform standard patient care and actualize personalized medicine

In a review study published in Frontiers in Bioengineering and Biotechnology, Francesca Taraballi, PhD, assistant professor of Orthopedic Surgery, and John P. Cooke, MD, PhD, professor of cardiovascular sciences at Houston Methodist, detail the advancements in the field of RNA therapeutics.
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Houston Methodist Researchers Generate and Validate Humanized Biomimetic Nanovesicles to Target Neurons – Two Firsts in Nanovesicle Theranostics

Francesca Taraballi, PhD, and Robert C. Krencik, PhD, are leading teams in a collaboration aimed at overcoming obstacles to the treatment of brain disorders. Taraballi’s team is focused on “functionalizing” lipid based nanovesicles (NV) to target specific neuronal cell types. Read now

Watch how we develop a vehicle for RNA therapeutics

Center for RNA Therapeutics – 29 set 2021


Watch how our bone regenerating membrane works

Houston Methodist Researchers Use Nanovesicles to Target Brain Cells

Houston Methodist Researchers Use Nanovesicles to Target Brain Cells
Houston Methodist scientists have created a first-of-its-kind method to deliver medicine to neural cells, a promising new avenue for treating brain disease and injury. Francesca Taraballi’s team showed its nanoparticle transport system crossed the blood-brain barrier in mice and delivered drugs that reduced brain lesions. Together with Krencik’s team used induced pluripotent stem cells (iPSCs) as a source of biological material to develop the biomimetic humanized neural nanovesicles, which can carry cargo such as medication, mRNA or diagnostic material. Read now